- Born: 1765, Brunswick County, Virginia 2837,2838,2886,2981,2983,2984
- Marriage (1): Elizabeth Harrison on 25 Oct 1787 in Greensville County, Virginia 1087,2837
- Marriage (2): Nancy Jones about 1803 in Virginia
- Died: 8 Jan 1855, Carroll County, Virginia at age 90 2837,2981,2984
- Buried: Branscome Cemetery, Dugspur, Carroll County, Virginia 2981
Isaac married Elizabeth Harrison, daughter of Thomas Harrison and Mary, on 25 Oct 1787 in Greensville County, Virginia 1087.,2837 (Elizabeth Harrison was born in 1766 2835 and died in 1802-1803 in Paul's Creek, Patrick (Now Carroll) County, Virginia 2837.)
Isaac next married Nancy Jones about 1803 in Virginia. (Nancy Jones was born in 1786 in Virginia 2838,2886,2984 and died on 13 May 1851 in Carroll County, Virginia.)
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