In Wissinoming, around 1892, a Mission of St. Stephen's, Bridesburg, was formed.  Services were first held in a private home, and then in an old school building which later became the old firehouse at Vankirk and Jackson.

In 1894, the Mission became St. Bartholomew's and was placed under the supervision of St. Mark's, Frankford.  A corner property was purchased at Comly and Ditman Streets in 1895, and a Chapel was erected on that site.  This was a small edifice, but through the years many improvements were made.  In 1905, an addition was made to the Chapel and, a little later, a basement was built under the Church.  A Charter was drawn up in September 1922, and St. Bartholomew's became a Parish of the Diocese.  In 1923, an old Army barracks was erected for temporary use in the rear of the rectory and was used for the growing Church School and also for social functions.

In 1928, the Parish House was built because more space was needed for a growing Parish.   The Church was in its "heyday."  With the new Parish House there was much activity.  Then the "Great Depression" came down with a bang!   The church didn't have much money, but they had a lot of people filled with spirit and enthusiasm.

During the World War II years, times were comparatively prosperous.  Many memorials were given to beautify the Church.  Brass candlesticks adorned the altar and very fine Eucharistic Vestments and Frontals to match were donated.  A Sanctuary Lamp was added.  Together with donations from parishioners, the Women's Guild doughnut sales paid off the mortgage on the Parish House.

Later on, the entrance to the Church was changed from the side to the rear.  This was a major improvement.  In 1960, a reredos was installed.  This particular type of altarpiece is called a "Triptych."  The side panels do not actually fold across the center, but are fixed to the wall.  The three panels suggest the Holy Trinity.  A Tabernacle for the "Reserved Sacrament" was given as a memorial.

On September 10, 1963 tragedy struck.  An electrical fire raged in the Parish House.  Precious vestments and altar hangings were rushed out and cleaned so they would not suffer smoke damage.  Fortunately, everything was repaired and life went on.